History of Hepatitis B Vaccine Discovery

History of Hepatitis B Vaccine Discovery - In 1965, Blumberg et al reported the first discovery of the hepatitis B surface antigen (HBsAg), also known as Australia antigen. A few years later, in 1970, Dane visualize hepatitis B virus (HBV) virion. Since then, great progress has been made ​​regarding the epidemiology, virology and treatment of viral hepatitis B. An estimated one-third of the world population has been infected with hepatitis B virus (HBV).

Approximately 350 million people are carriers for life, and only 2% of spontaneous seroconversion (heal itself without treatment) per year. Ongoing vaccination program seems promising in an effort to reduce the prevalence of HBV disease. Hepatitis B virus (HBV) is transmitted through blood or blood products and sexual (intercourse). The consequences of chronic hepatitis B trip active without treatment will develop into liver cirrhosis (damage to liver total) and progress toward liver cancer.

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